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TLR3 anticorps

TLR3 Reactivité: Humain, Souris, Rat IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7255782
  • Antigène Voir toutes TLR3 Anticorps
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Reactivité
    • 98
    • 67
    • 30
    • 6
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 85
    • 31
    • 5
    • 2
    Lapin
    Clonalité
    • 88
    • 35
    Polyclonal
    Conjugué
    • 53
    • 18
    • 15
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLR3 est non-conjugé
    Application
    • 85
    • 45
    • 38
    • 35
    • 23
    • 18
    • 16
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human TLR3 (NP_003256.1).
    Isotype
    IgG
    Top Product
    Discover our top product TLR3 Anticorps primaire
  • Indications d'application
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Autre désignation
    TLR3 (TLR3 Produits)
    Synonymes
    anticorps CD283, anticorps IIAE2, anticorps AI957183, anticorps zgc:123006, anticorps toll like receptor 3, anticorps toll-like receptor 3, anticorps TLR3, anticorps Tlr3, anticorps tlr3
    Sujet
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
    ID gène
    7098
    UniProt
    O15455
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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