TARDBP anticorps
Aperçu rapide pour TARDBP anticorps (ABIN7256938)
Antigène
Voir toutes TARDBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human TARDBP (NP_031401.1).
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Isotype
- IgG
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Indications d'application
- IHC 1:50-1:200 IF 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Autre désignation
- TARDBP
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Sujet
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
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ID gène
- 23435
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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