CAMLG anticorps

N° du produit ABIN7257333

Détail du produit anti-CAMLG anticorps

Antigène: CAMLG (Calcium Modulating Ligand (CAMLG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMLG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CAMLG (NP_001736.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CAMLG

Antigène: CAMLG (Calcium Modulating Ligand (CAMLG))

Autre désignation: CAMLG (CAMLG Produits)

Synonymes: anticorps MGC53900, anticorps CAML, anticorps AI385748, anticorps Camlg, anticorps Caml, anticorps calcium modulating ligand L homeolog, anticorps calcium modulating ligand, anticorps camlg.L, anticorps CAMLG, anticorps camlg, anticorps Caml, anticorps Camlg

Sujet: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Poids moléculaire:

Observed_MW: 38 kDa

Calculated_MW: 32 kDa

ID gène: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway