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DNASE1 anticorps

Cet anticorps anti-DNASE1 est un anticorps Lapin Polyclonal détectant DNASE1 dans IF. Adapté pour Rat et Souris.
N° du produit ABIN7257934

Aperçu rapide pour DNASE1 anticorps (ABIN7257934)

Antigène

Voir toutes DNASE1 Anticorps
DNASE1 (Deoxyribonuclease I (DNASE1))

Reactivité

  • 62
  • 25
  • 14
  • 13
Rat, Souris

Hôte

  • 60
  • 13
  • 1
Lapin

Clonalité

  • 63
  • 11
Polyclonal

Conjugué

  • 35
  • 11
  • 7
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DNASE1 est non-conjugé

Application

  • 62
  • 21
  • 21
  • 13
  • 13
  • 10
  • 9
  • 8
  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human DNASE1 (NP_005214.2).

    Isotype

    IgG
  • Indications d'application

    IF 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    DNASE1 (Deoxyribonuclease I (DNASE1))

    Autre désignation

    DNASE1

    Sujet

    This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    ID gène

    1773

    UniProt

    P24855
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