GRIA4 anticorps
Aperçu rapide pour GRIA4 anticorps (ABIN7258214)
Antigène
Voir toutes GRIA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human GRIA4 (NP_001070712.1).
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Isotype
- IgG
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Indications d'application
- WB 1:1000-1:4000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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Autre désignation
- GRIA4
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Sujet
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
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Poids moléculaire
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Observed_MW: 101 kDa
Calculated_MW: 49 kDa/100 kDa
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ID gène
- 2893
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UniProt
- P48058
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Pathways
- Signalisation PI3K-Akt
Antigène
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