Acetyl-CoA Carboxylase alpha anticorps

N° du produit ABIN7258506

Détail du produit anti-Acetyl-CoA Carboxylase alpha anticorps

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase alpha est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human ACACA

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Acetyl-CoA Carboxylase alpha

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Autre désignation: ACACA (ACACA Produits)

Synonymes: anticorps ACAC, anticorps ACACAD, anticorps ACC, anticorps ACC1, anticorps ACCA, anticorps A530025K05Rik, anticorps Acac, anticorps Acc1, anticorps Gm738, anticorps AT-ACC1, anticorps EMB22, anticorps EMBRYO DEFECTIVE 22, anticorps GK, anticorps GURKE, anticorps PAS3, anticorps PASTICCINO 3, anticorps acetyl-CoA carboxylase 1, anticorps acc, anticorps fj43d01, anticorps im:7138837, anticorps si:ch211-199d18.1, anticorps wu:fj43d01, anticorps acetyl-CoA carboxylase alpha, anticorps acetyl-Coenzyme A carboxylase alpha, anticorps acetyl-CoA carboxylase 1, anticorps ACACA, anticorps Acaca, anticorps ACC1, anticorps acaca

Sujet: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 240 kDa

Calculated_MW: 257 kDa/259 kDa/265 kDa/269 kDa

ID gène: 31

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, L'effet Warburg