DNMT1 anticorps
Aperçu rapide pour DNMT1 anticorps (ABIN7259344)
Antigène
Voir toutes DNMT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human DNMT1.
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Isotype
- IgG
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Indications d'application
- IHC 1:50-1:200 IF 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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Autre désignation
- DNMT1
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Sujet
- This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
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ID gène
- 1786
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UniProt
- P26358
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Pathways
- SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
Antigène
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