BRK1 anticorps

N° du produit ABIN7259616

Détail du produit anti-BRK1 anticorps

Antigène: BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRK1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human BRK1 (NP_060932.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BRK1

Antigène: BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))

Autre désignation: BRK1 (BRK1 Produits)

Synonymes: anticorps brk1, anticorps C22H3orf10, anticorps brick1, anticorps c3orf10, anticorps C3orf10, anticorps MDS027, anticorps hHBrk1, anticorps 6720456B07Rik, anticorps AW011779, anticorps ATBRK1, anticorps BRICK1, anticorps HSPC300, anticorps T9I22.8, anticorps T9I22_8, anticorps BRICK1, SCAR/WAVE actin-nucleating complex subunit, anticorps BRICK1, SCAR/WAVE actin nucleating complex subunit, anticorps brick 1, anticorps BRICK1, SCAR/WAVE actin-nucleating complex subunit S homeolog, anticorps BRICK1, anticorps brk1, anticorps BRK1, anticorps Brk1, anticorps brk1.S

Sujet: HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.

ID gène: 55845

UniProt: Q8WUW1

Pathways: Signalisation RTK