PCK1 anticorps
Aperçu rapide pour PCK1 anticorps (ABIN7260085)
Antigène
Voir toutes PCK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide of human PCK1 (NP_002582.3).
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Isotype
- IgG
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Indications d'application
- WB 1:1000-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
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Autre désignation
- PCK1
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Sujet
- This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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Poids moléculaire
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Observed_MW: 69 kDa
Calculated_MW: 34 kDa/69 kDa
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ID gène
- 5105
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UniProt
- P35558
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
Antigène
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