FANCD2 anticorps

N° du produit ABIN7260125

L’anticorps anti-FANCD2 Polyclonal produit chez le Lapin a été validé pour IF. Il convient pour la détection de FANCD2 dans des échantillons provenant de Humain. }

Aperçu rapide pour FANCD2 anticorps (ABIN7260125)

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCD2 est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-FANCD2 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human FANCD2 (NP_149075.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FANCD2

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Autre désignation: FANCD2

Sujet: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.

ID gène: 2177

UniProt: Q9BXW9

Pathways: Réparation de l'ADN