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GSTM3 anticorps

L’anticorps Lapin Polyclonal anti-GSTM3 a été validé pour WB. Il convient pour détecter GSTM3 dans des échantillons de Humain et Souris.
N° du produit ABIN7260901

Aperçu rapide pour GSTM3 anticorps (ABIN7260901)

Antigène

Voir toutes GSTM3 Anticorps
GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Reactivité

  • 36
  • 9
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Humain, Souris

Hôte

  • 19
  • 18
  • 2
Lapin

Clonalité

  • 23
  • 16
Polyclonal

Conjugué

  • 27
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GSTM3 est non-conjugé

Application

  • 23
  • 21
  • 12
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human GSTM3 (NP_000840.2).

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

    Autre désignation

    GSTM3

    Sujet

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

    Poids moléculaire

    Observed_MW: 25 kDa

    Calculated_MW: 26 kDa

    ID gène

    2947

    UniProt

    P21266
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