ATP7B anticorps

N° du produit ABIN7261626

Cet anticorps Lapin Polyclonal détecte spécifiquement ATP7B dans IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ATP7B anticorps (ABIN7261626)

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP7B est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-ATP7B anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ATP7B (NP_001230111.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATP7B

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Autre désignation: ATP7B

Sujet: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

ID gène: 540

UniProt: P35670

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process