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SF3B3 anticorps

Cet anticorps anti-SF3B3 est un anticorps Lapin Polyclonal détectant SF3B3 dans IHC. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7010966

Aperçu rapide pour SF3B3 anticorps (ABIN7010966)

Antigène

Voir toutes SF3B3 Anticorps
SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Reactivité

  • 48
  • 31
  • 16
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 46
  • 2
  • 1
Lapin

Clonalité

  • 38
  • 11
Polyclonal

Conjugué

  • 30
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp SF3B3 est non-conjugé

Application

  • 30
  • 20
  • 12
  • 9
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human SF3B3 (NP_036558.3).

    Isotype

    IgG
  • Indications d'application

    IHC 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

    Autre désignation

    SF3B3

    Sujet

    This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

    ID gène

    23450

    UniProt

    Q15393
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