Adenylosuccinate Lyase anticorps

N° du produit ABIN7262084

Cet anticorps Lapin Polyclonal détecte spécifiquement Adenylosuccinate Lyase dans WB et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Adenylosuccinate Lyase anticorps (ABIN7262084)

Antigène: Adenylosuccinate Lyase (ADSL)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylosuccinate Lyase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Adenylosuccinate Lyase anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ADSL (NP_000017.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:20-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Adenylosuccinate Lyase

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: ADSL

Sujet: The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 55 kDa

Calculated_MW: 48 kDa/54 kDa

ID gène: 158

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process