LIM Domain Binding 3 Protein anticorps

N° du produit ABIN7263475

Cet anticorps anti-LIM Domain Binding 3 Protein est un anticorps Lapin Polyclonal détectant LIM Domain Binding 3 Protein dans IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour LIM Domain Binding 3 Protein anticorps (ABIN7263475)

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Binding 3 Protein est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-LIM Domain Binding 3 Protein anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human LDB3 (NP_001073585.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LIM Domain Binding 3 Protein

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Autre désignation: LDB3

Sujet: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

ID gène: 11155

UniProt: O75112