Cofilin 2 anticorps
Aperçu rapide pour Cofilin 2 anticorps (ABIN7264069)
Antigène
Voir toutes Cofilin 2 (CFL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human CFL2 (NP_068733.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IF 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cofilin 2 (CFL2)
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Autre désignation
- CFL2
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Sujet
- This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
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Observed_MW: 18 kDa
Calculated_MW: 16 kDa/18 kDa
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ID gène
- 1073
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UniProt
- Q9Y281
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Pathways
- Caspase Cascade in Apoptosis
Antigène
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