ARHGEF3 anticorps

N° du produit ABIN7264537

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGEF3 dans WB et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ARHGEF3 anticorps (ABIN7264537)

Antigène: ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ARHGEF3 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ARHGEF3 (NP_062455.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARHGEF3

Antigène: ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Autre désignation: ARHGEF3

Sujet: Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 60 kDa

Calculated_MW: 36 kDa/59 kDa/60 kDa/63 kDa

ID gène: 50650

UniProt: Q9NR81

Pathways: Neurotrophin Signaling Pathway