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ARHGEF3 anticorps

ARHGEF3 Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7264537
  • Antigène Voir toutes ARHGEF3 Anticorps
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    Reactivité
    • 34
    • 4
    • 4
    • 1
    Humain, Souris
    Hôte
    • 31
    • 3
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARHGEF3 est non-conjugé
    Application
    • 25
    • 22
    • 19
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human ARHGEF3 (NP_062455.1).
    Isotype
    IgG
    Top Product
    Discover our top product ARHGEF3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    Autre désignation
    ARHGEF3 (ARHGEF3 Produits)
    Synonymes
    anticorps MGC82822, anticorps ARHGEF3, anticorps si:ch211-258l4.8, anticorps MGC108040, anticorps DKFZp459N027, anticorps GEF3, anticorps STA3, anticorps XPLN, anticorps 1200004I24Rik, anticorps 9830169H03Rik, anticorps C76747, anticorps Xpln, anticorps Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog, anticorps Rho guanine nucleotide exchange factor 3, anticorps Rho guanine nucleotide exchange factor (GEF) 3, anticorps Rho guanine nucleotide exchange factor (GEF) 3, gene 1, anticorps arhgef3.1.S, anticorps ARHGEF3, anticorps arhgef3, anticorps arhgef3.1, anticorps Arhgef3
    Sujet
    Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire

    Observed_MW: 60 kDa

    Calculated_MW: 36 kDa/59 kDa/60 kDa/63 kDa

    ID gène
    50650
    UniProt
    Q9NR81
    Pathways
    Neurotrophin Signaling Pathway
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