Separase anticorps (pSer1126)

N° du produit ABIN7265212

Détail du produit anti-Separase anticorps

Antigène: Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))

Épitope: pSer1126

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Separase est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4).

Isotype: IgG

Information d'application

Indications d'application: IF 1:20-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Separase

Antigène: Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))

Autre désignation: ESPL1 (ESPL1 Produits)

Synonymes: anticorps ESP1, anticorps SEPA, anticorps mp:zf637-3-001691, anticorps AL024103, anticorps AU045071, anticorps Cerp, anticorps PRCE, anticorps SSE, anticorps extra spindle pole bodies like 1, separase, anticorps extra spindle poles like 1, anticorps extra spindle pole bodies 1, separase, anticorps ESPL1, anticorps espl1, anticorps Espl1

Sujet: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

ID gène: 9700

UniProt: Q14674