PDGFRB anticorps (pTyr740)

N° du produit ABIN7265262

L’anticorps Lapin Polyclonal anti-PDGFRB a été validé pour WB. Il convient pour détecter PDGFRB dans des échantillons de Humain et Souris.

Aperçu rapide pour PDGFRB anticorps (pTyr740) (ABIN7265262)

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFRB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDGFRB anticorps

Épitope: pTyr740

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around Y740 of human PDGFR beta (NP_002600.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDGFRB

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Autre désignation: PDGFR beta

Sujet: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Poids moléculaire:

Observed_MW: 180 kDa

Calculated_MW: 37 kDa/123 kDa

ID gène: 5159

UniProt: P09619

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling