DLL4 anticorps (PE)
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- Antigène Voir toutes DLL4 Anticorps
- DLL4 (delta-Like 4 (DLL4))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DLL4 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- recombinant soluble human DLL4
- Clone
- MHD4-46
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product DLL4 Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-5 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Antigène
- DLL4 (delta-Like 4 (DLL4))
- Autre désignation
- DLL4 (DLL4 Produits)
- Synonymes
- anticorps hdelta2, anticorps Delta4, anticorps si:ch211-244p18.5, anticorps zgc:136596, anticorps delta like canonical Notch ligand 4, anticorps delta-like 4 (Drosophila), anticorps DLL4, anticorps Dll4, anticorps dll4
- Sujet
- Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
- ID gène
- 54567
- UniProt
- Q9NR61
- Pathways
- Signalisation Notch
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