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DLL4 anticorps (PE)

DLL4 Reactivité: Humain FACS Hôte: Souris Monoclonal MHD4-46 PE
N° du produit ABIN7013930
  • Antigène Voir toutes DLL4 Anticorps
    DLL4 (delta-Like 4 (DLL4))
    Reactivité
    • 50
    • 38
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 15
    • 8
    • 3
    • 1
    Souris
    Clonalité
    • 57
    • 25
    Monoclonal
    Conjugué
    • 47
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DLL4 est conjugé à/à la PE
    Application
    • 41
    • 28
    • 13
    • 13
    • 12
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    recombinant soluble human DLL4
    Clone
    MHD4-46
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product DLL4 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-5 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    DLL4 (delta-Like 4 (DLL4))
    Autre désignation
    DLL4 (DLL4 Produits)
    Synonymes
    anticorps hdelta2, anticorps Delta4, anticorps si:ch211-244p18.5, anticorps zgc:136596, anticorps delta like canonical Notch ligand 4, anticorps delta-like 4 (Drosophila), anticorps DLL4, anticorps Dll4, anticorps dll4
    Sujet
    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
    ID gène
    54567
    UniProt
    Q9NR61
    Pathways
    Signalisation Notch
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