CD32/CD16 anticorps (FITC)
Aperçu rapide pour CD32/CD16 anticorps (FITC) (ABIN7013996)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Ms CD16/CD32 FITC
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Specificité
- The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
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Purification
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogène
- Murine pre-B cells
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Isotype
- IgG2a lambda
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Indications d'application
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD32/CD16
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Autre désignation
- CD16/CD32
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Sujet
- CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Unlike human, the murine protein is expressed only as a transmembrane isoform. Also CD32 (FcgammaRII) is a low affinity receptor for IgG, but its affinity is lower than that of CD16. These receptors are expressed on monocytes/macrophages, NK cells, granulocytes, mast cells, dendritic cells, and B cells. Their role is to mediate adaptive immune responses through binding the antibody-antigen immunocomplexes, but their effect on the particular cell differs according to the cell type.,CD16, CD32, FcgammaRIII, FCgammaRII, FCGR3, FCGR2
Antigène
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