HSD11B2 anticorps (AA 151-250)

N° du produit ABIN701680

Cet anticorps Lapin Polyclonal détecte spécifiquement HSD11B2 dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Souris, Rat et Cheval et a été mentionné dans 4+ publications.

Aperçu rapide pour HSD11B2 anticorps (AA 151-250) (ABIN701680)

Antigène: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Reactivité: Souris, Rat, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD11B2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HSD11B2 anticorps

Épitope: AA 151-250

Réactivité croisée: Cheval, Souris, Rat

Homologie: Human,Dog

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSD11B2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-HSD11B2 (ABIN701680)

Ding, Shi, Han, Cui: "Regulation of glucocorticoid-related genes and receptors/regulatory enzyme expression in intrauterine growth restriction filial rats." dans: Life sciences, Vol. 150, pp. 61-6, (2016) (PubMed).

Wang, Zhang, Zhang, Luo, Ye, Guo, Chen, Huang: "Preeclampsia induced by cadmium in rats is related to abnormal local glucocorticoid synthesis in placenta." dans: Reproductive biology and endocrinology : RB&E, Vol. 12, pp. 77, (2015) (PubMed).

Xu, Zhao, Lin, Xiang, Wang, Ye, Huang: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." dans: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).

Détails sur HSD11B2

Antigène: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Autre désignation: HSD11B2

Sujet:

Synonyms: Corticosteroid 11-beta-dehydrogenase isozyme 2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type II, -HSD11 type II, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, 11-beta-HSD, HSD11B2, HSD11K

Background: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

ID gène: 3291

UniProt: P80365

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones