KISS1R anticorps (Extracellular)

N° du produit ABIN7043294

L’anticorps Lapin Polyclonal anti-KISS1R a été validé pour WB, IHC, IF, FACS et LCI. Il convient pour détecter KISS1R dans des échantillons de Humain.

Aperçu rapide pour KISS1R anticorps (Extracellular) (ABIN7043294)

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Détail du produit anti-KISS1R anticorps

Épitope: AA 292-305, Extracellular

Fonction: A Rabbit Polyclonal Antibody to Kisspeptin Receptor

Specificité: 3rd extracellular loop

Réactivité croisée: Humain, Rat

Homologie: mouse - 12,14 amino acid residues identical,Rat - 13

Attributs du produit: Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of the human kisspeptin receptor. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100

Application Dilutions Western blot wb: 1:500

Commentaires:

Cited Application: IHC|ICC

Negative Control: (ABIN7235833)

Blocking Peptide: (ABIN7235833)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur KISS1R

Antigène: KISS1R (KISS1 Receptor (KISS1R))

Autre désignation: KISS1R

Sujet: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12,The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

Alternative names: KISS1 Receptor (GPR54), Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12

ID gène: 84634

NCBI Accession: NM_032551

UniProt: Q969F8