Recombinant PRNP anticorps

N° du produit ABIN7072335

Cet anticorps anti-PRNP est un anticorps Souris Monoclonal détectant PRNP dans WB, ELISA, IHC et IP. Adapté pour Humain et Hamster.

Aperçu rapide pour Recombinant PRNP anticorps (ABIN7072335)

Antigène: PRNP (Prion Protein (PRNP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRNP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 3F4

Détail du produit anti-PRNP anticorps

Fonction: Anti-Prion [3F4], Mouse IgG1, kappa

Réactivité croisée: Humain

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: Hamster 263K PrPs.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The antibody binds specifically to prion, a misfolded protein that has the ability to enter healthy organisms and cause other misfolding of other proteins into their prion form. This plays an essential role in the pathogenesis of certain neurodegenerative disorders such as Creutzfeldt-Jakob disease (CJD), Gerstmann-Staussler syndrome (GSS) and bovine spongiform encephalopathy (BSE). These disorders are characterised by an accumulation of prion proteins in the brain, which have a disrupted secondary structure.

Commentaires:

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur PRNP

Antigène: PRNP (Prion Protein (PRNP))

Autre désignation: Prion

Sujet: Major prion protein, p27-30, CD30 antigen, prion protein PrP, prion-related protein

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation