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Recombinant PDCD1LG2 anticorps

Cet anticorps Lapin Chimeric détecte spécifiquement PDCD1LG2 dans WB, FACS, IP et BR. Il présente une réactivité envers Souris.
N° du produit ABIN7072432

Aperçu rapide pour Recombinant PDCD1LG2 anticorps (ABIN7072432)

Antigène

Voir toutes PDCD1LG2 Anticorps
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 101
  • 30
  • 10
  • 3
Souris

Hôte

  • 59
  • 45
  • 17
  • 1
Lapin

Clonalité

  • 80
  • 40
  • 1
Chimeric

Conjugué

  • 60
  • 11
  • 11
  • 10
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PDCD1LG2 est non-conjugé

Application

  • 73
  • 54
  • 35
  • 28
  • 19
  • 15
  • 11
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

Clone

TY25
  • Fonction

    Anti-PD-L2 [TY25], Rabbit IgG, kappa

    Specificité

    This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1.

    Attributs du produit

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogène

    This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.

    Isotype

    IgG kappa
  • Indications d'application

    This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.

    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    Autre désignation

    PD-L2

    Sujet

    CD273, B7-DC, PDL2, B7DC, programmed death ligand 2, CD273, Pdcd1lg2

    UniProt

    Q9WUL5
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