Recombinant PDCD1LG2 anticorps
Aperçu rapide pour Recombinant PDCD1LG2 anticorps (ABIN7072432)
Antigène
Voir toutes PDCD1LG2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-PD-L2 [TY25], Rabbit IgG, kappa
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Specificité
- This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1.
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Attributs du produit
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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Purification
- Protein A affinity purified
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Immunogène
- This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.
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Isotype
- IgG kappa
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Indications d'application
- This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.
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Commentaires
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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Autre désignation
- PD-L2
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Sujet
- CD273, B7-DC, PDL2, B7DC, programmed death ligand 2, CD273, Pdcd1lg2
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UniProt
- Q9WUL5
Antigène
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