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Recombinant PDCD1LG2 anticorps

L’anticorps Rat Monoclonal anti-PDCD1LG2 a été validé pour WB, FACS, IP et BR. Il convient pour détecter PDCD1LG2 dans des échantillons de Souris.
N° du produit ABIN7072433

Aperçu rapide pour Recombinant PDCD1LG2 anticorps (ABIN7072433)

Antigène

Voir toutes PDCD1LG2 Anticorps
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 102
  • 30
  • 10
  • 3
Souris

Hôte

  • 60
  • 46
  • 16
  • 1
Rat

Clonalité

  • 80
  • 40
  • 2
Monoclonal

Conjugué

  • 60
  • 11
  • 11
  • 10
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PDCD1LG2 est non-conjugé

Application

  • 74
  • 54
  • 35
  • 28
  • 19
  • 15
  • 11
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

Clone

TY25
  • Fonction

    Anti-PD-L2 [TY25], Rat IgG2a, kappa

    Specificité

    This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1.

    Attributs du produit

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogène

    This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.

    Isotype

    IgG2a kappa
  • Indications d'application

    This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    Autre désignation

    PD-L2

    Sujet

    CD273, B7-DC, PDL2, B7DC, programmed death ligand 2, CD273, Pdcd1lg2

    UniProt

    Q9WUL5
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