Recombinant DARC anticorps (N-Term)

N° du produit ABIN7072437

Cet anticorps anti-DARC Chimeric Lapin (Clone 2C3) (ABIN7072437) détecte spécifiquement DARC dans WB, ELISA, FACS, BP et Inh. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant DARC anticorps (N-Term) (ABIN7072437)

Antigène: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp DARC est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Blocking Peptide (BP), Inhibition (Inh)

Clone: 2C3

Détail du produit anti-DARC anticorps

Épitope: N-Term

Fonction: Anti-DARC [2C3], Rabbit IgG, kappa

Specificité:

The antibody specifically binds to the pentapeptide FEDVW of the Duffy Antigen Receptor for Chemokines (DARC). The epitope is located on the N-terminal region on the RBC surface membrane. DARC is a glycoprotein chemokine receptor and the only known receptor for Plasmodium vivax.

Application Notes original Clone: The original antibody (mouse IgG1) was generated and used successfully in ELISA, FC, and inhibition assays, blocking DARC and IL-8 binding. The antibody's epitope was also characterized (Wasniowska et al., 2002, PMID: 12164140). This antibody was successfully used in a WB (Czerwinski et al., 2007 (PMID: 17382291), Smolarek et al., 2015 (PMID: 25706384)). This antibody was successfully used to inhibit P. Vivax invasion (Russell et al., 2011 (PMID: 21768300), Urusova et al., 2019 (PMID: 31133752)).

Attributs du produit: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: CHO cells transfected with cDNA encoding the Duffy glycoprotein.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur DARC

Antigène: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Autre désignation: DARC

Sujet: Fy6, Duffy Antigen Receptor for Chemokines, NaM185-2C3

UniProt: Q4VBN9