Recombinant MME anticorps

N° du produit ABIN7072451

L’anticorps Lapin Chimeric anti-MME a été validé pour WB, IP et IF. Il convient pour détecter MME dans des échantillons de Humain.

Aperçu rapide pour Recombinant MME anticorps (ABIN7072451)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp MME est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: NL-1

Détail du produit anti-MME anticorps

Fonction: Anti-CD10 [NL-1], Rabbit IgG, kappa

Specificité: This antibody reacts with human CD10. CD10 is a widely-expressed cell-surface metalloprotease, responsible for the cleavage of multiple peptide hormones at target tissues. CD10 is also a common marker for acute lymphocytic leukaemia.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: BALB/c mice were immunised with acute lymphocytic leukaemia cells from a human leukaemia patient. Splenocytes were obtained from immunised mice and fused with MOPC-21 NS/1 myeloma cells to generate a hybridoma.

Isotype: IgG kappa

Information d'application

Indications d'application: NL-1 was shown to react with several leukaemic cell lines using immune adherence assays (Ueda et al, 1982). These authors also confirmed that NL-1 is specific for CD10 using IP.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10

Classe de substances: Chemical

Sujet: Neprilysin, Cluster of Differentiation 10, Membrane metallo-endopeptidase, MME, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Common acute lymphocytic leukaemia antigen, CALLA, Skin fibroblast elastase, SFE, CMT2T, SCA43, Atriopeptidase, Enkephalinase

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration