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Recombinant Transferrin Receptor anticorps

Cet anticorps anti-Transferrin Receptor est un anticorps Lapin Chimeric détectant Transferrin Receptor dans FACS et Dep. Adapté pour Souris.
N° du produit ABIN7072542

Aperçu rapide pour Recombinant Transferrin Receptor anticorps (ABIN7072542)

Antigène

Voir toutes Transferrin Receptor (TFRC) Anticorps
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 249
  • 108
  • 51
  • 8
  • 6
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
Souris

Hôte

  • 164
  • 128
  • 48
  • 4
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 243
  • 99
  • 3
Chimeric

Conjugué

  • 148
  • 32
  • 28
  • 22
  • 16
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Transferrin Receptor est non-conjugé

Application

  • 206
  • 149
  • 103
  • 69
  • 64
  • 52
  • 34
  • 25
  • 19
  • 18
  • 12
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Depletion (Dep)

Clone

R17 217-1-3
  • Fonction

    Anti-Transferrin receptor [R17 217.1.3], Rabbit IgG, kappa

    Specificité

    The transferrin receptor is necessary for cellular iron uptake by the process of receptor-mediated endocytosis. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.

    Attributs du produit

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogène

    The antibody was obtained from a fusion of the murine myeloma S 194/5.XXO.BU. 1 with spleen cells from a BDIX rat immunized with the Friend erythroleukemia 745.6.

    Isotype

    IgG kappa
  • Indications d'application

    R17 217.1.3 was used in conjunction with flow cytometry to identify murine hematopoietic progenitor cells expressing the transferrin receptor (Lesley et al, 1984). Injection of mice with R17 217.1.3 results in CD71+ erythroid splenocyte cell depletion (Torow et al, 2015).

    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    Autre désignation

    Transferrin receptor

    Sujet

    CD71, Transferrin receptor protein 1, TR, , TfR1, Trfr

    Pathways

    Transition Metal Ion Homeostasis
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