Recombinant IL-9 anticorps
Aperçu rapide pour Recombinant IL-9 anticorps (ABIN7072551)
Antigène
Voir toutes IL-9 (IL9) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-IL-9 [D9302C12], Rabbit IgG, kappa
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Specificité
- This antibody is specific for murine IL-9.
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Attributs du produit
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Original Species of Ab: Hamster, Armenian
Original Format of Ab: IgG
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Purification
- Protein A affinity purified
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Immunogène
- This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.
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Isotype
- IgG kappa
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Indications d'application
- In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).
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Commentaires
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This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- IL-9 (IL9) (Interleukin 9 (IL9))
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Autre désignation
- IL-9
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Sujet
- Interleukin-9, IL9, Cytokine P40, T-cell growth factor P40
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UniProt
- P15247
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Pathways
- Signalistation JAK/STAT
Antigène
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