Recombinant MARCO anticorps (Extracellular Domain)
Aperçu rapide pour Recombinant MARCO anticorps (Extracellular Domain) (ABIN7072581)
Antigène
Voir toutes MARCO AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Fonction
- Anti-MARCO [PLK1], Rabbit IgG, kappa
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Specificité
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This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples.
Application Notes original Clone: The specificity of this antibody was confirmed in an IF experiment where the antibody stained alveolar macrophages for MACRO (Arredouani et al., 2005). Tissue samples prepared in acetone and paraformaldehyde were also successfully immunohistochemically stained (Arredouani et al., 2005, Martens et al., 2006). The antibody was also capable of weak staining of alveolar macrophages in flow cytometry (Palecanda and Kobzik, 2001). In IP experiments, the antibody immunoprecipitates MARCO from lysates obtained from COS cells transfected with human MARCO (Arredouani et al., 2005).
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Attributs du produit
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.
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Purification
- Protein A affinity purified
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Immunogène
- The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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OriginalSpeciesName: Mouse
OriginalFormat: IgG3
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
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Autre désignation
- MARCO
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Sujet
- SCARA2, macrophage receptor MARCO, macrophage receptor with collagenous structure, scavenger receptor class A member 2, PLK-1, PLK 1
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UniProt
- Q9UEW3
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Pathways
- Activation of Innate immune Response
Antigène
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