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Recombinant CCR9 anticorps (N-Term)

Cet anticorps anti-CCR9 est un anticorps Lapin Chimeric détectant CCR9 dans FACS et Neut. Adapté pour Souris.
N° du produit ABIN7072662

Aperçu rapide pour Recombinant CCR9 anticorps (N-Term) (ABIN7072662)

Antigène

Voir toutes CCR9 Anticorps
CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 47
  • 41
  • 6
  • 3
  • 3
Souris

Hôte

  • 52
  • 14
  • 8
  • 4
  • 1
Lapin

Clonalité

  • 51
  • 27
Chimeric

Conjugué

  • 35
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CCR9 est non-conjugé

Application

  • 47
  • 22
  • 20
  • 13
  • 13
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS), Neutralization (Neut)

Clone

9B1
  • Épitope

    • 15
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Fonction

    Anti-CCR9 [9B1], Rabbit IgG, kappa

    Specificité

    9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells.

    Attributs du produit

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogène

    This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.

    Isotype

    IgG kappa
  • Indications d'application

    This antibody is recommended for the detection and analysis of CCR9 via flow cytometry (Farazuddin et al., 2019). Furthermore, it was demonstrated that this 9B1 antibody was capable of neutralizing CCR9 function, as it inhibited CCL25-induced calcium mobilization in L1.2-CCR9 cells (Rivera-Nieves et al., 2006).

    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

    Autre désignation

    CCR9

    Sujet

    CD199, C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CDw199, 9B-1

    UniProt

    Q9WUT7
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