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alpha Actinin anticorps

Cet anticorps anti-alpha Actinin est un anticorps Lapin Polyclonal détectant alpha Actinin dans WB, IHC et IF. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7073023

Aperçu rapide pour alpha Actinin anticorps (ABIN7073023)

Antigène

Voir toutes alpha Actinin (ACTN) Anticorps
alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Reactivité

  • 10
  • 8
  • 8
  • 4
  • 1
Humain, Souris, Rat

Hôte

  • 9
  • 2
Lapin

Clonalité

  • 9
  • 2
Polyclonal

Conjugué

  • 7
  • 2
  • 2
Cet anticorp alpha Actinin est non-conjugé

Application

  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  •  Réactivité croisée

    Souris, Rat

    Purification

    Affinity purification

    Immunogène

    KLH conjugated Synthetic peptide corresponding to Human ACTN1
  • Indications d'application

    WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS, pH 7.4, 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C
  • Antigène

    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

    Autre désignation

    alpha Actinin

    Sujet

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

    Poids moléculaire

    103 kDa

    ID gène

    109711

    NCBI Accession

    NP_001093

    UniProt

    P12814

    Pathways

    Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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