alpha Actinin anticorps

N° du produit ABIN7073023

Cet anticorps anti-alpha Actinin Polyclonal Lapin (ABIN7073023) détecte spécifiquement alpha Actinin dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour alpha Actinin anticorps (ABIN7073023)

Antigène: alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Actinin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-alpha Actinin anticorps

Réactivité croisée: Souris, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Human ACTN1

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur alpha Actinin

Antigène: alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Autre désignation: alpha Actinin

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

Poids moléculaire: 103 kDa

ID gène: 109711

NCBI Accession: NP_001093

UniProt: P12814

Pathways: Cell-Cell Junction Organization, Negative Regulation of Transporter Activity