CDKN2C anticorps

N° du produit ABIN7073645

Cet anticorps Lapin Polyclonal détecte spécifiquement CDKN2C dans WB. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour CDKN2C anticorps (ABIN7073645)

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDKN2C anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse CDKN2C

Information d'application

Indications d'application: WB (M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CDKN2C

Antigène: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Autre désignation: p18 INK4c

Sujet: Cyclin-dependent kinase 4 inhibitor C is an enzyme encoded by the CDKN2C gene. The protein is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

Poids moléculaire: 18 kDa

ID gène: 12580

NCBI Accession: NP_001288297

UniProt: Q60772

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases