GTF2B anticorps

N° du produit ABIN7074034

Cet anticorps anti-GTF2B est un anticorps Polyclonal produit chez le Lapin, détectant GTF2B dans WB, IHC et IF. Convient pour Humain, Souris et Rat.

Aperçu rapide pour GTF2B anticorps (ABIN7074034)

Antigène: GTF2B (General Transcription Factor IIB (GTF2B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GTF2B anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TFIIB

Information d'application

Indications d'application: WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:500-1:1500/1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur GTF2B

Antigène: GTF2B (General Transcription Factor IIB (GTF2B))

Autre désignation: TFIIB

Sujet: General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA .Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex .Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle . Associates with chromatin to core promoter- specific regions .Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner,Modulates transcription start site selection . Exhibits also autoacetyltransferase activity that contributes to the activated transcription .

Poids moléculaire: 35 kDa

ID gène: 229906

NCBI Accession: NP_663521

UniProt: P62915