HSPD1 anticorps
Aperçu rapide pour HSPD1 anticorps (ABIN7074167)
Antigène
Voir toutes HSPD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse HSP60
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Indications d'application
- WB (H,M,R) 1:3000-1:10000, IHC/IF ,IEM (H,M,R) 1:500-1:1000/1:500-1:1000/1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
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Autre désignation
- Hsp60
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Sujet
- Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60's bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetes, stress response, cancer and certain types of immunological disorders.
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Poids moléculaire
- 60 kDa
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ID gène
- 15510
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NCBI Accession
- NP_034607
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UniProt
- P63038
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Pathways
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Antigène
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