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CD74 anticorps

CD74 Reactivité: Souris, Rat IF, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7074245
  • Antigène Voir toutes CD74 Anticorps
    CD74 (HLA-DR-gamma (CD74))
    Reactivité
    • 183
    • 64
    • 12
    • 11
    Souris, Rat
    Hôte
    • 121
    • 79
    • 4
    • 2
    Lapin
    Clonalité
    • 138
    • 66
    • 2
    Polyclonal
    Conjugué
    • 70
    • 17
    • 16
    • 10
    • 10
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD74 est non-conjugé
    Application
    • 125
    • 111
    • 77
    • 43
    • 36
    • 36
    • 30
    • 27
    • 18
    • 14
    • 13
    • 11
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC)
     Réactivité croisée
    Rat
    Purification
    Affinity purification
    Immunogène
    Recombinant protein corresponding to Mouse CD74
    Top Product
    Discover our top product CD74 Anticorps primaire
  • Indications d'application
    IHC/IF (M,R) 1:1000-1:4000/1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    CD74 (HLA-DR-gamma (CD74))
    Autre désignation
    CD74 (CD74 Produits)
    Synonymes
    anticorps DHLAG, anticorps HLADG, anticorps II, anticorps Ia-GAMMA, anticorps CLIP, anticorps Ii, anticorps INVG34, anticorps Iclp-1, anticorps iclp1, anticorps wu:fb11f09, anticorps wu:fb12a01, anticorps wu:fb13d06, anticorps wu:fk94e07, anticorps Iclp-2, anticorps cd74, anticorps iclp2, anticorps zgc:123161, anticorps CD74 molecule, anticorps CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), anticorps CD74 molecule, major histocompatibility complex, class II invariant chain a, anticorps CD74 molecule, major histocompatibility complex, class II invariant chain b, anticorps CD74, anticorps Cd74, anticorps cd74a, anticorps cd74b
    Sujet
    CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized.
    ID gène
    16149
    NCBI Accession
    NP_001036070
    UniProt
    P04441
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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