HIF3A anticorps

N° du produit ABIN7074273

L’anticorps anti-HIF3A Polyclonal Lapin est utilisé pour la détection de HIF3A dans des échantillons de Souris et Rat. Il a été validé pour IHC et IF.

Aperçu rapide pour HIF3A anticorps (ABIN7074273)

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIF3A est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-HIF3A anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse HIF3 alpha

Information d'application

Indications d'application: IHC/IF (M,R) 1:800-1:3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur HIF3A

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Autre désignation: HIF3 alpha/IPAS

Sujet: Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

ID gène: 53417

NCBI Accession: NP_001156422

UniProt: Q0VBL6

Pathways: L'effet Warburg