MECOM anticorps

N° du produit ABIN7074575

Cet anticorps Lapin Polyclonal détecte spécifiquement MECOM dans WB, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MECOM anticorps (ABIN7074575)

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECOM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MECOM anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse EVI1

Information d'application

Indications d'application: WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000/1:700-1:1400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MECOM

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Autre désignation: EVI1

Sujet: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Poids moléculaire: 118 kDa

ID gène: 14013

NCBI Accession: NP_067417

UniProt: P14404