RBM45 anticorps
Aperçu rapide pour RBM45 anticorps (ABIN7075477)
Antigène
Voir toutes RBM45 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse RB-1
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Indications d'application
- IHC/IF (M,R) 1:700-1:1400/1:500-1:2500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- RBM45 (RNA Binding Motif Protein 45 (RBM45))
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Autre désignation
- RB-1
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Sujet
- RB1 belongs to the retinoblastoma protein family. It is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.
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ID gène
- 19645
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NCBI Accession
- NP_033055
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UniProt
- P13405
Antigène
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