S100A9 anticorps
Aperçu rapide pour S100A9 anticorps (ABIN7075497)
Antigène
Voir toutes S100A9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse S100A9
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Indications d'application
- WB (M,R) 1:300-1:800, IHC/IF (M,R) 1:1500-1:3000/1:750-1:1500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
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Autre désignation
- S100A9
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Sujet
- Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
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Poids moléculaire
- 13 kDa
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ID gène
- 20202
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NCBI Accession
- NP_001268781
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UniProt
- P31725
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Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
Antigène
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