SIN3A anticorps

N° du produit ABIN7075609

Cet anticorps anti-SIN3A est un anticorps Lapin Polyclonal détectant SIN3A dans IF et IHC. Adapté pour Souris et Rat.

Aperçu rapide pour SIN3A anticorps (ABIN7075609)

Antigène: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3A est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-SIN3A anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse mSin3A

Information d'application

Indications d'application: IHC/IF (M,R) 1:100-1:200/1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SIN3A

Antigène: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Autre désignation: mSin3A

Sujet: The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.

ID gène: 20466

NCBI Accession: NP_001103820

UniProt: Q60520

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha