SUV39H2 anticorps
Aperçu rapide pour SUV39H2 anticorps (ABIN7075771)
Antigène
Voir toutes SUV39H2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse SUV39H2
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Indications d'application
- IHC/IF (H,M,R) 1:1000-1:4000/1:500-1:3000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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Autre désignation
- KMT1B/SUV39H2
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Sujet
- Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.
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ID gène
- 64707
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NCBI Accession
- NP_073561
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UniProt
- Q9EQQ0
Antigène
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