TSG101 anticorps (N-Term)
Aperçu rapide pour TSG101 anticorps (N-Term) (ABIN7076083)
Antigène
Voir toutes TSG101 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée
- Humain, Rat
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Purification
- Affinity purification
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Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse TSG101(N-terminal)
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Indications d'application
- WB (H,M,R) 1: 500-1: 1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Autre désignation
- TSG101
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Sujet
- The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression
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Poids moléculaire
- 46 kDa
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ID gène
- 22088
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NCBI Accession
- NP_068684
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UniProt
- Q61187
Antigène
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