SORD anticorps (AA 251-357) (HRP)

N° du produit ABIN704735

L’anticorps Lapin Polyclonal anti-SORD a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter SORD dans des échantillons de Souris.

Aperçu rapide pour SORD anticorps (AA 251-357) (HRP) (ABIN704735)

Antigène: SORD (Sorbitol Dehydrogenase (SORD))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SORD est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SORD anticorps (HRP)

Épitope: AA 251-357

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Sorbitol Dehydrogenase

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SORD

Antigène: SORD (Sorbitol Dehydrogenase (SORD))

Autre désignation: SDH/Sorbitol Dehydrogenase

Sujet:

Synonyms: L iditol 2 dehydrogenase, SDH, SORD 1, SORD, SORD1. DHSO_HUMAN

Background: Sorbitol dehydrogenase (SDH), a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, converts sorbitol to fructose strictly using NAD(+) as coenzyme. SDH is expressed almost ubiquitously in all mammalian tissues. The enzyme has attracted considerable interest due to its implication in the development of diabetic complications as the polyol pathway is particularly active in hyperglycemic states. Although SORD is closely related to the class I long-chain alcohol dehydrogenases, it differs in substrate specificity, catalyzing polyols such as sorbitol and xylitol but having no activity towards primary alcohols.

ID gène: 6390