CD8 alpha anticorps (APC)
Aperçu rapide pour CD8 alpha anticorps (APC) (ABIN7076714)
Antigène
Voir toutes CD8 alpha (CD8A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD8a APC Antibody
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Attributs du produit
- The clone SK1 specifically binds with a 32-34 kDa type I transmembrane glycoprotein of human cells commonly known as CD8a. It is a member of immunoglobulin superfamily. The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Human peripheral blood T lymphocytes
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Isotype
- IgG1, kappa
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Indications d'application
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Autre désignation
- CD8a
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ID gène
- 925
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NCBI Accession
- NM_001768
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UniProt
- P01732
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Pathways
- TCR Signaling
Antigène
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