MED1 anticorps (AA 1321-1420) (Biotin)

N° du produit ABIN705478

Cet anticorps Lapin Polyclonal détecte spécifiquement MED1 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour MED1 anticorps (AA 1321-1420) (Biotin) (ABIN705478)

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MED1 anticorps (Biotin)

Épitope: AA 1321-1420

Homologie: Human,Mouse,Rat,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRAP220/MED1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MED1

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Autre désignation: TRAP220

Sujet:

Synonyms: CRSP1, CRSP200, DRIP205, DRIP230, MED1, MED1_HUMAN, Mediator complex subunit 1, Mediator of RNA polymerase II transcription subunit 1, p53 regulatory protein RB18A, PBP, Peroxisome prolerator-activated receptor-binding protein, PPAR binding protein, PPAR-binding protein, PPARBP, PPARGBP, RB18A, Thyroid hormone receptor-associated protein complex 220 kDa component, Thyroid receptor-interacting protein 2, TR-interacting protein 2, TRAP220, TRIP-2, TRIP2, Vitamin D receptor-interacting protein complex component DRIP205, Activator-recruited cofactor 205 kDa component, ARC205.

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

ID gène: 5469

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha