UGT2B4 anticorps (AA 111-210)
Aperçu rapide pour UGT2B4 anticorps (AA 111-210) (ABIN705506)
Antigène
Voir toutes UGT2B4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 111-210
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Homologie
- Human,Sheep
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human UGT2B4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))
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Autre désignation
- UGT2B4
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Sujet
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Synonyms: HLUG25, Hyodeoxycholic acid, UDP glucuronosyltransferase 2 family polypeptide B4, UDP glucuronosyltransferase 2B4 precursor, UDP glucuronyltransferase family 2 beta 4, UDP glycosyltransferase 2 family polypeptide B4, UDP glycosyltransferase, UDPGT, UDPGTh 1, UDPGTh1, UGT2B11, UGT2B4, UD2B4_HUMAN.
Background: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.
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ID gène
- 7363
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Pathways
- Steroid Hormone Biosynthesis
Antigène
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